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Scientist, Human Pluripotent Stem Cell Biology

Aspect Biosystems

Aspect Biosystems

Vancouver, BC, Canada
Posted on Saturday, July 6, 2024

We are seeking a Scientist, Human Pluripotent Stem Cell Biology to join Aspect’s Therapeutic Cell Platform team. Reporting to the Senior Director, Therapeutic Cell Platforms, the Scientist, Human Pluripotent Stem Cell Biology will play a pivotal role in developing bioprinted tissue therapeutics from human pluripotent stem cells (hPSCs). This is an exciting opportunity to work closely with a multidisciplinary team to develop bioprinted tissue therapeutics that could transform the way we develop medicines and treat diseases.

Responsibilities

  • Independently design, plan, and execute experiments and assays to support the development of bioprinted tissue therapeutic programs.
  • Conduct comprehensive assessments of hPSC lines, including phenotypic, genetic, and functional evaluations.
  • Develop and refine methods to enhance process efficiency and quality.
  • Perform and optimize hPSC differentiation protocols to generate specific cell types for therapeutic applications.
  • Expertly culture and maintain hPSCs, ensuring high cell quality and viability.
  • Work closely with Process Development teams to design, execute scale-up/scale-out strategies, and draft Standard Operating Procedures (SOPs) for use of cells in bioprinted tissue therapeutics.
  • Collaborate with tissue engineers, biomaterials experts, and biologists to optimize cell functions in bioprinted tissues.
  • Generate experimental reports and present data to key internal and external stakeholders.
  • Maintain clear and rigorous experimental records, including electronic laboratory notebooks.

Qualifications

  • Education + Experience: PhD in biology, biotechnology, life sciences or related field, or a MSc with at least 5 years of industry experience.
  • Cell Line Knowledge: Hands on experience in handlining hPSCs, cell-based assays, Flow cytometry, and cell culture.
  • Laboratory Skills: In-depth technical experience in flow cytometry, immunostaining, and molecular biology techniques such as nucleic acid extractions, qPCR, library constructions for RNA-Seq. Knowledge in bioinformatics analyses is a plus.

Who You Are

  • Intellectually Curious: You have a burning desire to learn more and aren’t afraid to ask questions.
  • Problem Solver: You love immersing yourself in difficult technical problems and coming up with solutions that work. You think outside the box and use your experience and intuition to identify when such solutions are realistic.
  • Detail-Oriented & Meticulously Organized: You have outstanding attention to detail and take pride in your work. You can multitask, prioritize competing deadlines, and have a track record for delivering work on time.
  • Thrive in Ambiguity: You are highly adaptable, agile, and poised when faced with change, ambiguity, and competing priorities.
  • Collaborative: You thrive in a multi-disciplinary team environment and believe that we can get further, faster by working together.
  • Effective Communicator: You are an active listener who can effectively communicate to different audiences in diverse situations.
  • Go-Getter: You work with a sense of urgency, are results-driven, and thrive in a fast-paced, interdisciplinary, and entrepreneurial environment. You are willing to roll up your sleeves and do what it takes to get the job done.

The hiring range for this role is $77,000 - $110,000, annually. Our ranges are based on market data. Offered salaries will be based on a combination of factors including, but not limited to, job-related knowledge, skills, education, and experience. For candidates who exceed role requirements, we are open to exploring above-range offers. Note that base salary is just one part of the overall compensation at Aspect. Members of the Aspect team also receive equity, a comprehensive benefits package, and support for continuous learning and career progression.

Who We Are

Aspect Biosystems is a Canadian biotechnology company creating bioprinted tissue therapeutics to transform how we treat disease. Our bold team of innovators and entrepreneurs have joined us from all over the globe to create a new class of regenerative medicine and work towards a future where our bioprinted tissues are used to save lives and make people healthier. We are endlessly curious and wildly passionate about what we do. Every person on our team is a key contributor to our success and is eager to roll up their sleeves to make a difference in the ever-changing world of biotech. If you are committed to making a real impact and accelerating the development of life-changing therapies, we want to hear from you!

Curious about our current perks and benefits? Learn more here.

At Aspect Biosystems, our strength has always been in our diversity. Different people, thinking differently, unified in creating a world that is better for us all. We are committed to creating an inclusive environment for everyone on our team. All aspects of employment — including the decision to hire, promote, discipline, or terminate — are based on merit, competence, performance, and business needs. We do not discriminate on the basis of race, colour, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, provincial, or local law.

If you're interested in joining our team but don't see a job posting that matches your experience or background, we encourage you to submit a general application to be considered for future opportunities!